Mechanosensing in T Lymphocyte Activation

Mechanical forces play an increasingly recognized role in modulating cell function. This report demonstrates mechanosensing by T cells, using polyacrylamide gels presenting ligands to CD3 and CD28. Naive CD4 T cells exhibited stronger activation, as measured by attachment and secretion of IL-2, with...

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Autori principali: Judokusumo, Edward, Tabdanov, Erdem, Kumari, Sudha, Dustin, Michael L., Kam, Lance C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2012
Soggetti:
Biophysical Letter
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260692/
https://ncbi.nlm.nih.gov/pubmed/22339876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.12.011
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