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DNA glycosylases: in DNA repair and beyond
The base excision repair machinery protects DNA in cells from the damaging effects of oxidation, alkylation, and deamination; it is specialized to fix single-base damage in the form of small chemical modifications. Base modifications can be mutagenic and/or cytotoxic, depending on how they interfere...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer-Verlag
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3260424/ https://ncbi.nlm.nih.gov/pubmed/22048164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-011-0347-4 |
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