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The Scaffolding Protein Dlg1 Is a Negative Regulator of Cell-Free Virus Infectivity but Not of Cell-to-Cell HIV-1 Transmission in T Cells

BACKGROUND: Cell-to-cell virus transmission of Human immunodeficiency virus type-1 (HIV-1) is predominantly mediated by cellular structures such as the virological synapse (VS). The VS formed between an HIV-1-infected T cell and a target T cell shares features with the immunological synapse (IS). We...

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Main Authors: Nzounza, Patrycja, Chazal, Maxime, Guedj, Chloé, Schmitt, Alain, Massé, Jean-Marc, Randriamampita, Clotilde, Pique, Claudine, Ramirez, Bertha Cecilia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260186/
https://ncbi.nlm.nih.gov/pubmed/22272285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030130
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