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Two-Drug Antimicrobial Chemotherapy: A Mathematical Model and Experiments with Mycobacterium marinum

Multi-drug therapy is the standard-of-care treatment for tuberculosis. Despite this, virtually all studies of the pharmacodynamics (PD) of mycobacterial drugs employed for the design of treatment protocols are restricted to single agents. In this report, mathematical models and in vitro experiments...

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Detalhes bibliográficos
Main Authors: Ankomah, Peter, Levin, Bruce R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257304/
https://ncbi.nlm.nih.gov/pubmed/22253599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002487
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