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Synaptonemal complex protein SYCP3 impairs mitotic recombination by interfering with BRCA2
The meiosis-specific synaptonemal complex protein SYCP3 has been reported to be aberrantly expressed in tumours. However, in contrast to its well-defined function in meiosis, its possible role in mitotic cells is entirely unknown. Here, we show that SYCP3 is expressed in a range of primary tumours a...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3246250/ https://ncbi.nlm.nih.gov/pubmed/22116401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.221 |
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