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Inhibition of Wnt signaling by cucurbitacin B in breast cancer cells: Reduction of Wnt associated proteins and reduced translocation of galectin-3-mediated β-catenin to the nucleus

The cucurbitacins are tetracyclic triterpenes found in plants of the family Cucurbitaceae. Cucurbitacins have been shown to have anticancer and anti-inflamatory activities. We investigated the anticancer activity of cucurbitacin B extracted from Thai medicinal plant Trichosanthes cucumerina Linn. Ce...

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書誌詳細
主要な著者: Dakeng, Sumana, Duangmano, Suwit, Jiratchariyakul, Weena, U-Pratya, Yaowalak, Bögler, Oliver, Patmasiriwat, Pimpicha
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245346/
https://ncbi.nlm.nih.gov/pubmed/21866566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23326
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