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VISA is Required for B Cell Expression of TLR7

B cells play a critical role in the initialization and development of the Systemic Lupus Erythematosus (SLE) that is dependent on the expression of the endosomal ssRNA receptor TLR7. Previous studies have established that B cell expression of TLR7 is controlled by the Type I IFN secreted by Plasmacy...

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Bibliographic Details
Main Authors: Xu, Liang-Guo, Jin, Lei, Zhang, Bi-Cheng, Akerlund, Janie L., Shu, Hong-Bing, Cambier, John C.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244560/
https://ncbi.nlm.nih.gov/pubmed/22105994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100918
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