Identification of Sequence Variants in Genetic Disease-Causing Genes Using Targeted Next-Generation Sequencing

BACKGROUND: Identification of gene variants plays an important role in research on and diagnosis of genetic diseases. A combination of enrichment of targeted genes and next-generation sequencing (targeted DNA-HiSeq) results in both high efficiency and low cost for targeted sequencing of genes of int...

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Bibliographic Details
Main Authors: Wei, Xiaoming, Ju, Xiangchun, Yi, Xin, Zhu, Qian, Qu, Ning, Liu, Tengfei, Chen, Yang, Jiang, Hui, Yang, Guanghui, Zhen, Ruan, Lan, Zhangzhang, Qi, Ming, Wang, Jinming, Yang, Yi, Chu, Yuxing, Li, Xiaoyan, Guang, Yanfang, Huang, Jian
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244462/
https://ncbi.nlm.nih.gov/pubmed/22216297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029500
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