PAH Particles Perturb Prenatal Processes and Phenotypes: Protection from Deficits in Object Discrimination Afforded by Dampening of Brain Oxidoreductase Following In Utero Exposure to Inhaled Benzo(a)pyrene

The wild-type (WT) Cpr(lox/lox) (cytochrome P(450) oxidoreductase, Cpr) mouse is an ideal model to assess the contribution of P(450) enzymes to the metabolic activation and disposition of environmental xenobiotics. In the present study, we examined the effect of in utero exposure to benzo(a)pyrene [...

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Detalhes bibliográficos
Main Authors: Li, Zhu, Chadalapaka, Gayathri, Ramesh, Aramandla, Khoshbouei, Habibeh, Maguire, Mark, Safe, Stephen, Rhoades, Raina E., Clark, Ryan, Jules, George, McCallister, Monique, Aschner, Michael, Hood, Darryl B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Neurotoxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243744/
https://ncbi.nlm.nih.gov/pubmed/21987461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr261
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