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Integrin adhesion and force coupling are independently regulated by localized PtdIns(4,5)(2) synthesis
The 90-kDa isoform of the lipid kinase PIP kinase Type I γ (PIPKIγ) localizes to focal adhesions (FAs), where it provides a local source of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P(2)). Although PtdIns(4,5)P(2) regulates the function of several FA-associated molecules, the role of the FA-...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3243596/ https://ncbi.nlm.nih.gov/pubmed/21926969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.332 |
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