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The Goldilocks Principle and Antibiotic Resistance in Bacteria

We have designed and fabricated a micro-ecology to mimic the naturally occurring bacterial culture, which includes stress gradient, metapopulation and cellular motility. In this micro-ecology, we show it is possible to fix resistance to the mutagenic antibiotic ciprofloxacin in wild-type E. coli wit...

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Bibliographic Details
Main Authors: Zhang, Qiucen, Robin, Kristelle, Liao, David, Lambert, Guillaume, Austin, Robert H.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235521/
https://ncbi.nlm.nih.gov/pubmed/22085251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp200274r
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