Protein Phosphatase 5 Mediates Lipid Metabolism through Reciprocal Control of Glucocorticoid Receptor and Peroxisome Proliferator-activated Receptor-γ (PPARγ)

Glucocorticoid receptor-α (GRα) and peroxisome proliferator-activated receptor-γ (PPARγ) regulate adipogenesis by controlling the balance between lipolysis and lipogenesis. Here, we show that protein phosphatase 5 (PP5), a nuclear receptor co-chaperone, reciprocally modulates the lipometabolic activ...

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Bibliographische Detailangaben
Hauptverfasser: Hinds, Terry D., Stechschulte, Lance A., Cash, Harrison A., Whisler, Donald, Banerjee, Ananya, Yong, Weidong, Khuder, Saja S., Kaw, Meenakshi K., Shou, Weinian, Najjar, Sonia M., Sanchez, Edwin R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Metabolism
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234872/
https://ncbi.nlm.nih.gov/pubmed/21994940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.311662
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