Population pharmacokinetics of oral high-dose busulfan in adult patients undergoing hematopoietic stem cell transplantation

BACKGROUND AND THE PURPOSE OF THE STUDY: Many factors have been reported that contribute to the wide intra- and inter-patient variability of Busulfan (Bu) disposition. The purpose of this study was to develop a population pharmacokinetic model and to determine the covariates affecting the pharmacoki...

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Main Authors: Hadjibabaie, M., Rahimian, S., Jahangard-Rafsanjani, Z., Amini, M., Alimoghaddam, K., Iravani, M., Ghavamzadeh, A., Sadrai, S.
Format: Artigo
Sprog:Inglês
Udgivet: Tehran University of Medical Sciences 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232103/
https://ncbi.nlm.nih.gov/pubmed/22615660
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