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Minocycline-induced attenuation of iron overload and brain injury following experimental intracerebral hemorrhage

BACKGROUND AND PURPOSE: Brain iron overload plays a detrimental role in brain injury after intracerebral hemorrhage (ICH). A recent study found that minocycline acts as an iron chelator and reduces iron-induced neuronal death in vitro. The present study investigated if minocycline reduces iron overl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhao, Fan, Hua, Ya, He, Yangdong, Keep, Richard F, Xi, Guohua
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226873/
https://ncbi.nlm.nih.gov/pubmed/21998050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.623926
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