Angiopoietin-1 Gene Therapy Attenuates Hypertension and Target Organ Damage in Nitric Oxide Synthase Inhibited Spontaneously Hypertensive Rats

BACKGROUND AND OBJECTIVES: In our previous study, we found that the gene transfer of a potent derivative of cartilage oligomeric matrix protein Angiopoietin-1 (COMP-Ang-1) substantially prevented hypertension, microvascular rarefaction, and target organ damage in spontaneously hypertensive rats (SHR...

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Hauptverfasser: Suh, Wonhee, Lee, Jung-Sun, Kim, Koung Li, Song, Sun-Hwa, Koh, Gou Young, Kim, Duk-Kyung
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Society of Cardiology 2011
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221901/
https://ncbi.nlm.nih.gov/pubmed/22125558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4070/kcj.2011.41.10.590
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