Effects of DPP-4 Inhibitors on the Heart in a Rat Model of Uremic Cardiomyopathy

BACKGROUND: Uremic cardiomyopathy contributes substantially to mortality in chronic kidney disease (CKD) patients. Glucagon-like peptide-1 (GLP-1) may improve cardiac function, but is mainly degraded by dipeptidyl peptidase-4 (DPP-4). METHODOLOGY/PRINCIPAL FINDINGS: In a rat model of chronic renal f...

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Hlavní autoři: Chaykovska, Lyubov, von Websky, Karoline, Rahnenführer, Jan, Alter, Markus, Heiden, Susi, Fuchs, Holger, Runge, Frank, Klein, Thomas, Hocher, Berthold
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220703/
https://ncbi.nlm.nih.gov/pubmed/22125632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027861
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