Membrane Depolarization Increases Membrane PtdIns(4,5)P(2) Levels through Mechanisms Involving PKC βII and PI4 Kinase

In a previous study, we showed that membrane depolarization induced elevation of membrane phosphatidylinositol 4,5-bisphosphates (PtdIns(4,5)P(2), also known as PIP(2)) and subsequently increased the KCNQ2/Q3 currents expressed in Xenopus oocytes through increased PI4 kinase activity. In this study,...

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Autors principals: Chen, Xingjuan, Zhang, Xuan, Jia, Caixia, Xu, Jiaxi, Gao, Haixia, Zhang, Guohong, Du, Xiaona, Zhang, Hailin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220586/
https://ncbi.nlm.nih.gov/pubmed/21953466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.289090
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