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SPARC promotes pericyte recruitment via inhibition of endoglin-dependent TGF-β1 activity

Pericytes migrate to nascent vessels and promote vessel stability. Recently, we reported that secreted protein acidic and rich in cysteine (SPARC)–deficient mice exhibited decreased pericyte-associated vessels in an orthotopic model of pancreatic cancer, suggesting that SPARC influences pericyte beh...

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Autors principals: Rivera, Lee B., Brekken, Rolf A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216331/
https://ncbi.nlm.nih.gov/pubmed/21708981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201011143
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