Enhanced Activity of Meprin-α, a Pro-Migratory and Pro-Angiogenic Protease, in Colorectal Cancer

Meprin-α is a metalloprotease overexpressed in cancer cells, leading to the accumulation of this protease in a subset of colorectal tumors. The impact of increased meprin-α levels on tumor progression is not known. We investigated the effect of this protease on cell migration and angiogenesis in vit...

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Bibliographic Details
Main Authors: Lottaz, Daniel, Maurer, Christoph A., Noël, Agnès, Blacher, Silvia, Huguenin, Maya, Nievergelt, Alexandra, Niggli, Verena, Kern, Alexander, Müller, Stefan, Seibold, Frank, Friess, Helmut, Becker-Pauly, Christoph, Stöcker, Walter, Sterchi, Erwin E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214016/
https://ncbi.nlm.nih.gov/pubmed/22096485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026450
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