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Mono-(2-ethylhexyl) Phthalate Directly Alters the Expression of Leydig Cell Genes and CYP17 Lyase Activity in Cultured Rat Fetal Testis

Exposure to phthalates in utero alters fetal rat testis gene expression and testosterone production, but much remains to be done to understand the mechanisms underlying the direct action of phthalate within the fetal testis. We aimed to investigate the direct mechanisms of action of mono-(2-ethylhex...

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Hlavní autoři: Chauvigné, François, Plummer, Simon, Lesné, Laurianne, Cravedi, Jean-Pierre, Dejucq-Rainsford, Nathalie, Fostier, Alexis, Jégou, Bernard
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210143/
https://ncbi.nlm.nih.gov/pubmed/22087261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027172
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