Analysis of Influenza Virus Hemagglutinin Receptor Binding Mutants with Limited Receptor Recognition Properties and Conditional Replication Characteristics

To examine the range of selective processes that potentially operate when poorly binding influenza viruses adapt to replicate more efficiently in alternative environments, we passaged a virus containing an attenuating mutation in the hemagglutinin (HA) receptor binding site in mice and characterized...

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Bibliografski detalji
Glavni autori: Bradley, Konrad C., Galloway, Summer E., Lasanajak, Yi, Song, Xuezheng, Heimburg-Molinaro, Jamie, Yu, Hai, Chen, Xi, Talekar, Ganesh R., Smith, David F., Cummings, Richard D., Steinhauer, David A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Virus-Cell Interactions
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209400/
https://ncbi.nlm.nih.gov/pubmed/21917953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05570-11
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