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Novel anticancer polymeric conjugates of activated nucleoside analogs

Inherent or therapy-induced drug resistance is a major clinical setback in cancer treatment. The extensive usage of cytotoxic nucleobases and nucleoside analogs in chemotherapy also results in the development of specific mechanisms of drug resistance; such as nucleoside transport or activation defic...

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Autores principales: Senanayake, Thulani H., Warren, Galya, Vinogradov, Serguei V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200571/
https://ncbi.nlm.nih.gov/pubmed/21863885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200173e
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