Inhibition of Dengue Virus Infections in Cell Cultures and in AG129 Mice by a Small Interfering RNA Targeting a Highly Conserved Sequence

The dengue viruses (DENVs) exist as numerous genetic strains that are grouped into four antigenically distinct serotypes. DENV strains from each serotype can cause severe disease and threaten public health in tropical and subtropical regions worldwide. No licensed antiviral agent to treat DENV infec...

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Detalhes bibliográficos
Main Authors: Stein, David A., Perry, Stuart T., Buck, Michael D., Oehmen, Christopher S., Fischer, Matthew A., Poore, Elizabeth, Smith, Jessica L., Lancaster, Alissa M., Hirsch, Alec J., Slifka, Mark K., Nelson, Jay A., Shresta, Sujan, Früh, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196423/
https://ncbi.nlm.nih.gov/pubmed/21795337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05298-11
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