Functional Characterization of a Ficolin-mediated Complement Pathway in Amphioxus

The ficolin-mediated complement pathway plays an important role in vertebrate immunity, but it is not clear whether this pathway exists in invertebrates. Here we identified homologs of ficolin pathway components from the cephalochordate amphioxus and investigated whether they had been co-opted into...

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Main Authors: Huang, Huiqing, Huang, Shengfeng, Yu, Yingcai, Yuan, Shaochun, Li, Rui, Wang, Xin, Zhao, Hongchen, Yu, Yanhong, Li, Jun, Yang, Manyi, Xu, Liqun, Chen, Shangwu, Xu, Anlong
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196118/
https://ncbi.nlm.nih.gov/pubmed/21832079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.245944
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