Functional Characterization of a Ficolin-mediated Complement Pathway in Amphioxus

The ficolin-mediated complement pathway plays an important role in vertebrate immunity, but it is not clear whether this pathway exists in invertebrates. Here we identified homologs of ficolin pathway components from the cephalochordate amphioxus and investigated whether they had been co-opted into...

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Detalles Bibliográficos
Main Authors: Huang, Huiqing, Huang, Shengfeng, Yu, Yingcai, Yuan, Shaochun, Li, Rui, Wang, Xin, Zhao, Hongchen, Yu, Yanhong, Li, Jun, Yang, Manyi, Xu, Liqun, Chen, Shangwu, Xu, Anlong
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196118/
https://ncbi.nlm.nih.gov/pubmed/21832079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.245944
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