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Improving the prediction of disease-related variants using protein three-dimensional structure
BACKGROUND: Single Nucleotide Polymorphisms (SNPs) are an important source of human genome variability. Non-synonymous SNPs occurring in coding regions result in single amino acid polymorphisms (SAPs) that may affect protein function and lead to pathology. Several methods attempt to estimate the imp...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3194195/ https://ncbi.nlm.nih.gov/pubmed/21992054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S4-S3 |
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