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Characterization of bbtTICAM from amphioxus suggests the emergence of a MyD88-independent pathway in basal chordates
The MyD88-independent pathway, one of the two crucial TLR signaling routes, is thought to be a vertebrate innovation. However, a novel Toll/interleukin-1 receptor (TIR) adaptor, designated bbtTICAM, which was identified in the basal chordate amphioxus, links this pathway to invertebrates. The protei...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3193451/ https://ncbi.nlm.nih.gov/pubmed/21931360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.156 |
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