Cyclic strain upregulates VEGF and attenuates proliferation of vascular smooth muscle cells

OBJECTIVE: Vascular smooth muscle cell (VSMC) hypertrophy and proliferation occur in response to strain-induced local and systemic inflammatory cytokines and growth factors which may contribute to hypertension, atherosclerosis, and restenosis. We hypothesize VSMC strain, modeling normotensive arteri...

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Hauptverfasser: Schad, Joseph F, Meltzer, Kate R, Hicks, Michael R, Beutler, David S, Cao, Thanh V, Standley, Paul R
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189867/
https://ncbi.nlm.nih.gov/pubmed/21929819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-824X-3-21
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