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Fast and accurate prediction of protein side-chain conformations

Summary: We developed a fast and accurate side-chain modeling program [Optimized Side Chain Atomic eneRgy (OSCAR)-star] based on orientation-dependent energy functions and a rigid rotamer model. The average computing time was 18 s per protein for 218 test proteins with higher prediction accuracy (1....

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Hlavní autoři: Liang, Shide, Zheng, Dandan, Zhang, Chi, Standley, Daron M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187653/
https://ncbi.nlm.nih.gov/pubmed/21873640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr482
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