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Bacterial Display and Screening of Posttranslationally Thioether-Stabilized Peptides
A major hurdle in the application of therapeutic peptides is their rapid degradation by peptidases. Thioether bridges effectively protect therapeutic peptides against breakdown, thereby strongly increasing bioavailability, enabling oral and pulmonary delivery and potentially significantly optimizing...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3187086/ https://ncbi.nlm.nih.gov/pubmed/21821759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.05550-11 |
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