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Mutagenesis and Functional Analysis of Ion Channels Heterologously Expressed in Mammalian Cells
We will demonstrate how to study the functional effects of introducing a point mutation in an ion channel. We study G protein-gated inwardly rectifying potassium (referred to as GIRK) channels, which are important for regulating the excitability of neurons. There are four different mammalian GIRK ch...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MyJove Corporation
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3185640/ https://ncbi.nlm.nih.gov/pubmed/20972402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2189 |
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