Drosophila syndecan regulates tracheal cell migration by stabilizing Robo levels

Here we identify a new role for Syndecan (Sdc), the only transmembrane heparan sulphate proteoglycan in Drosophila, in tracheal development. Sdc is required cell autonomously for efficient directed migration and fusion of dorsal branch cells, but not for dorsal branch formation per se. The cytoplasm...

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Detalhes bibliográficos
Main Authors: Schulz, Joachim G, Ceulemans, Helga, Caussinus, Emmanuel, Baietti, Maria F, Affolter, Markus, Hassan, Bassem A, David, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185339/
https://ncbi.nlm.nih.gov/pubmed/21836636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.153
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