Drosophila syndecan regulates tracheal cell migration by stabilizing Robo levels

Here we identify a new role for Syndecan (Sdc), the only transmembrane heparan sulphate proteoglycan in Drosophila, in tracheal development. Sdc is required cell autonomously for efficient directed migration and fusion of dorsal branch cells, but not for dorsal branch formation per se. The cytoplasm...

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Hlavní autoři: Schulz, Joachim G, Ceulemans, Helga, Caussinus, Emmanuel, Baietti, Maria F, Affolter, Markus, Hassan, Bassem A, David, Guido
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
Témata:
Scientific Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185339/
https://ncbi.nlm.nih.gov/pubmed/21836636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.153
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