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c-Rel Deficiency Increases Caspase-4 Expression and Leads to ER Stress and Necrosis in EBV-Transformed Cells

LMP1-mediated activation of nuclear factor of kappaB (NF-κB) is critical for the ligand independent proliferation and cell survival of in vitro EBV-transformed lymphoblastoid cell lines (LCLs). Previous experiments revealed that a majority of LMP1-dependent responses are regulated by NF-κB. However,...

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Sonraí Bibleagrafaíochta
Main Authors: Valentín-Acevedo, Aníbal, Sinquett, Frank L., Covey, Lori R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184984/
https://ncbi.nlm.nih.gov/pubmed/21984918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025467
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