Disruption of cell-matrix interactions by heparin enhances mesenchymal progenitor adipocyte differentiation

Differentiation of marrow-derived mesenchymal progenitors to either the osteoblast or adipocyte lineage is reciprocally regulated. Factors that promote osteoblastogenesis inhibit adipogenesis, while adipogenic factors are inhibitory to osteoblast differentiation. Heparin, a soluble glycosaminoglycan...

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Bibliografiske detaljer
Main Authors: Luo, Weijun, Shitaye, Hailu, Friedman, Michael, Bennett, Christina N., Miller, Joshua, MacDougald, Ormond A., Hankenson, Kurt D.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179914/
https://ncbi.nlm.nih.gov/pubmed/18674534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.07.003
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