Bound Water at Protein-Protein Interfaces: Partners, Roles and Hydrophobic Bubbles as a Conserved Motif

BACKGROUND: There is a great interest in understanding and exploiting protein-protein associations as new routes for treating human disease. However, these associations are difficult to structurally characterize or model although the number of X-ray structures for protein-protein complexes is expand...

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Bibliografiska uppgifter
Huvudupphovsmän: Ahmed, Mostafa H., Spyrakis, Francesca, Cozzini, Pietro, Tripathi, Parijat K., Mozzarelli, Andrea, Scarsdale, J. Neel, Safo, Martin A., Kellogg, Glen E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178540/
https://ncbi.nlm.nih.gov/pubmed/21961043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024712
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