The role of tumor necrosis factor-α and TNF-α receptors in cerebral arteries following cerebral ischemia in rat

BACKGROUND: Tumour necrosis factor-α (TNF-α) is a pleiotropic pro-inflammatory cytokine, which is rapidly upregulated in the brain after injury. TNF-α acts by binding to its receptors, TNF-R1 (p55) and TNF-R2 (p75), on the cell surface. The aim of this study was first to investigate if there is alte...

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Bibliographic Details
Main Authors: Maddahi, Aida, Kruse, Lars S, Chen, Qing-Wen, Edvinsson, Lars
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177895/
https://ncbi.nlm.nih.gov/pubmed/21871121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-107
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