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The Characteristic Long-Term Upregulation of Hippocampal NF-κB Complex in PTSD-Like Behavioral Stress Response Is Normalized by High-Dose Corticosterone and Pyrrolidine Dithiocarbamate Administered Immediately after Exposure

Nuclear factor-κB (NF-κB) is a ubiquitously expressed transcription factor for genes involved in cell survival, differentiation, inflammation, and growth. This study examined the role of NF-κB pathway in stress-induced PTSD-like behavioral response patterns in rats. Immunohistochemical technique was...

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Detalhes bibliográficos
Main Authors: Cohen, Hagit, Kozlovsky, Nitsan, Matar, Michael A, Zohar, Joseph, Kaplan, Zeev
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176566/
https://ncbi.nlm.nih.gov/pubmed/21734649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.118
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