A Novel Mechanism of High-Level, Broad-Spectrum Antibiotic Resistance Caused by a Single Base Pair Change in Neisseria gonorrhoeae

The MtrC-MtrD-MtrE multidrug efflux pump of Neisseria gonorrhoeae confers resistance to a diverse array of antimicrobial agents by transporting these toxic compounds out of the gonococcus. Frequently in gonococcal strains, the expression of the mtrCDE operon is differentially regulated by both a rep...

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Bibliographic Details
Main Authors: Ohneck, Elizabeth A., Zalucki, Yaramah M., Johnson, Paul J. T., Dhulipala, Vijaya, Golparian, Daniel, Unemo, Magnus, Jerse, Ann E., Shafer, William M.
Format: Artigo
Language:Inglês
Published: American Society of Microbiology 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175627/
https://ncbi.nlm.nih.gov/pubmed/21933917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00187-11
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