Developmentally programmed assembly of higher order telomerase complexes with distinct biochemical and structural properties

In Euplotes crassus, telomerase is responsible for telomere maintenance during vegetative growth and de novo telomere synthesis during macronuclear development. Here we show that telomerase in the vegetative stage of the life cycle exists as a 280-kD complex that can add telomeric repeats only onto...

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Bibliographic Details
Main Authors: Greene, Eric C., Shippen, Dorothy E.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1998
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC317169/
https://ncbi.nlm.nih.gov/pubmed/9744868
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