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Developmentally programmed assembly of higher order telomerase complexes with distinct biochemical and structural properties
In Euplotes crassus, telomerase is responsible for telomere maintenance during vegetative growth and de novo telomere synthesis during macronuclear development. Here we show that telomerase in the vegetative stage of the life cycle exists as a 280-kD complex that can add telomeric repeats only onto...
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Hauptverfasser: | , |
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Format: | Artigo |
Sprache: | Inglês |
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Cold Spring Harbor Laboratory Press
1998
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC317169/ https://ncbi.nlm.nih.gov/pubmed/9744868 |
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