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Clodronate Liposomes Improve Metabolic Profile and Reduce Visceral Adipose Macrophage Content in Diet-Induced Obese Mice

BACKGROUND: Obesity-related adipose inflammation has been thought to be a causal factor for the development of insulin resistance and type 2 diabetes. Infiltrated macrophages in adipose tissue of obese animals and humans are an important source for inflammatory cytokines. Clodronate liposomes can ab...

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Detalhes bibliográficos
Main Authors: Feng, Bin, Jiao, Ping, Nie, Yaohui, Kim, Thomas, Jun, Dale, van Rooijen, Nico, Yang, Zaiqing, Xu, Haiyan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171445/
https://ncbi.nlm.nih.gov/pubmed/21931688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024358
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