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Deletion of the Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Auxiliary Subunit TRIP8b Impairs Hippocampal I(h) Localization and Function and Promotes Antidepressant Behavior in Mice

Output properties of neurons are greatly shaped by voltage-gated ion channels, whose biophysical properties and localization within axodendritic compartments serve to significantly transform the original input. The hyperpolarization-activated current, I(h), is mediated by hyperpolarization-activated...

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Détails bibliographiques
Auteurs principaux: Lewis, Alan S., Vaidya, Sachin P., Blaiss, Cory A., Liu, Zhiqiang, Stoub, Travis R., Brager, Darrin H., Chen, Xiangdong, Bender, Roland A., Estep, Chad M., Popov, Andrey B., Kang, Catherine E., Van Veldhoven, Paul P., Bayliss, Douglas A., Nicholson, Daniel A., Powell, Craig M., Johnston, Daniel, Chetkovich, Dane M.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169171/
https://ncbi.nlm.nih.gov/pubmed/21593326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0936-11.2011
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