Melarsoprol Cyclodextrin Inclusion Complexes as Promising Oral Candidates for the Treatment of Human African Trypanosomiasis

Human African trypanosomiasis (HAT), or sleeping sickness, results from infection with the protozoan parasites Trypanosoma brucei (T.b.) gambiense or T.b.rhodesiense and is invariably fatal if untreated. There are 60 million people at risk from the disease throughout sub-Saharan Africa. The infectio...

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Main Authors: Rodgers, Jean, Jones, Amy, Gibaud, Stéphane, Bradley, Barbara, McCabe, Christopher, Barrett, Michael P., Gettinby, George, Kennedy, Peter G. E.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167784/
https://ncbi.nlm.nih.gov/pubmed/21909447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001308
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