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HIV-1 Replication and Latency Are Regulated by Translational Control of Cyclin T1

HIV exploits cellular proteins during its replicative cycle and latent infection. The positive transcription elongation factor, P-TEFb, is a key cellular transcription factor critical for these viral processes and is a drug target. During viral replication P-TEFb is recruited via interactions of its...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hoque, Mainul, Shamanna, Raghavendra A., Guan, Deyu, Pe’ery, Tsafi, Mathews, Michael B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164259/
https://ncbi.nlm.nih.gov/pubmed/21763496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.03.060
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