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Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk

BACKGROUND: The Tec family kinases are implicated in signaling from lymphocyte antigen receptors and are activated following phosphorylation by Src kinases. For most Tec kinases, this activation requires an interaction between their pleckstrin homology (PH) domains and the products of phosphoinositi...

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Bibliographic Details
Main Authors: Chamorro, Mario, Czar, Michael J, Debnath, Jayanta, Cheng, Genhong, Lenardo, Michael J, Varmus, Harold E, Schwartzberg, Pamela L
Format: Artigo
Language:Inglês
Published: BioMed Central 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC31577/
https://ncbi.nlm.nih.gov/pubmed/11353545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-2-3
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