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Dehydroepiandrosterone (DHEA) replacement decreases insulin resistance and lowers inflammatory cytokines in aging humans

Plasma dehydroepiandrosterone (DHEA) decreases ~80% between ages 25 and 75 yr. In a preliminary study, we found that 6 mo of DHEA replacement improved insulin action in elderly individuals. The purpose of the present larger, randomized double-blind study was to determine whether a longer period of D...

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Bibliographic Details
Main Authors: Weiss, Edward P., Villareal, Dennis T., Fontana, Luigi, Han, Dong-Ho, Holloszy, John O.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156603/
https://ncbi.nlm.nih.gov/pubmed/21566261
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