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The HP1a Disordered C-terminus and Chromo Shadow Domain Cooperate to Select Target Peptide Partners

Drosophila melanogaster Heterochromatin Protein 1a (HP1a) is essential for compacted heterochromatin structure and associated gene silencing. Its chromo shadow domain (CSD) is well-known for binding to peptides that contain a PXVXL motif. Heterochromatin protein 2 (HP2) is a nonhistone chromosomal p...

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書誌詳細
主要な著者: Mendez, Deanna L., Kim, Daesung, Chruszcz, Maksymilian, Stephens, Gena E., Minor, Wladek, Khorasanizadeh, Sepideh, Elgin, Sarah C.R.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154745/
https://ncbi.nlm.nih.gov/pubmed/21472955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201000598
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