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The emerging role of epigenetic mechanisms in the etiology of neural tube defects

The molecular requirements for neural tube closure are complex. This is illustrated by the occurrence of neural tube defects (NTDs) in many genetic mouse mutants, which implicate a variety of genes, pathways and cellular functions. NTDs are also prevalent birth defects in humans, affecting around 1...

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Bibliographic Details
Main Authors: Greene, Nicholas DE, Stanier, Philip, Moore, Gudrun E
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154428/
https://ncbi.nlm.nih.gov/pubmed/21613818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.6.7.16400
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