Decreased SH3BP2 Inhibits Osteoclast Differentiation and Function

Germline mutations in SH3BP2 gene have been identified in patients with cherubism, a skeletal disorder characterized by excessive osteoclastic bone resorption that is limited to the mandible and maxilla. We previously demonstrated that SH3BP2 overexpression in Raw264.7 cells increased RANKL-induced...

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Bibliografiske detaljer
Main Authors: Kawamoto, Teruya, Fan, Chun, Gaivin, Robert J, Levine, Michael A, Lietman, Steven A
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150609/
https://ncbi.nlm.nih.gov/pubmed/21448930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.21408
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